RESULTS: Patients after implantation of total knee endoprosthesis have a better quality of life, i.e. As an instruments of this research are used standardized SF-36 questionnaire for assessing the quality of life and overall health status and a modified questionnaire on the socio-demographic characteristics of the respondents. RESPONDENTS AND RESEARCH METHODS: There were 30 subjects of both genders with knee joint disease enrolled in the study, who were treated with the surgical course at the Orthopedics clinic and the traumatology of the UKCS by implanting a total endoprosthesis, from the beginning of April until the end of October 2018. The aim of this study is to examine are there any differences in the quality of people's life before and after implantation of total knee endoprosthesis. Thanks to the achievements of modern medicine, in patients with advanced osteoarthritis of the hip or knee it is possible to replace the diseased joint with an endoprosthesis, with very good long-term results related to pain reduction and function improvement. Those are the main cause of chronic pain and disability in the modern world. INTRODUCTION: Diseases of the locomotor system or musculoskeletal disease are on the rise, mainly due to the ageing of the population but also due to lifestyle changes. CONCLUSIONS: In most segments of the qual ity of l ife, better results were showed in subjects who had undergone physical therapy. However, the physical therapy showed a positive effect in the group II at performance of daily routine, connected to failing health, related to th e quantity of time during their work p= 0.019, while the subjects of the group I, according to this statistics, achieve significantly less than they would like p= 0.038. The physical therapy had no influence on the limitations of their daily routine and it was not found any statistically important difference between the group I and the group II. 63,3% in the group I and 70% in the group II. RESULTS: Concerning the gender, in both groups were predominant female subjects i.e. The quality of life of the patients with multiple sclerosis in both examined groups, was evaluated by MSQUL-54 questionnaire, which is a multidimensional measure of quality of life related to health which connects generic and MS-specific items in one instrument. In the group I are the subjects who had not any physical treatment in the prior year while in the group II are the subjects who had undergone therapeutic physical therapy. The subjects were divided in two almost equal groups (n=30). METHODS: In the research were included 60 data subjects who satisfied the criteria for inclusion in the research. The objective of our study is to find out the influence of physical therapy in patients with multiple sclerosis and importance of physical therapy for quality of life in the persons with multiple sclerosis. INTRODUCTION: Multiple sclerosis (MS) is a chronic inflammatory, non-communicable, progressive multifocal demyelinating autoimmune disease of central nervous system (CMS) which can be noticed by various neurological symptoms.
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